In vivo and Postmortem Clinicoanatomical Correlations in Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17

BACKGROUND: Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) is associated with mutations in the Microtubule-Associated Protein Tau(MAPT) gene or the Progranulin(PGRN) gene. MAPT mutations lead to widespread deposition of hyperphosphorylated tau protein (FTDP-17T). PGRN mut...

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Autores principales: Ghetti, Bernardino, Spina, Salvatore, Murrell, Jill R., Huey, Edward D., Pietrini, Pietro, Sweeney, Brian, Wassermann, Eric M., Keohane, Catherine, Farlow, Martin R., Grafman, Jordan
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2008
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Various Markers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826454/
https://ncbi.nlm.nih.gov/pubmed/18322394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000113706
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