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Etiology and Pathophysiology of Frontotemporal Dementia, Parkinson Disease and Alzheimer Disease: Lessons from Genetic Studies

Genetic studies have led to major discoveries in the pathogenesis of various neurodegenerative diseases. Ubiquitin-positive familial frontotemporal dementia was recently found to be caused by mutations in the progranulin gene (PGRN), and the major constituent of the inclusions, TDP-43, was subsequen...

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Bibliografski detalji
Glavni autori: Wider, Christian, Wszolek, Zbigniew K.
Format: Artigo
Jezik:Inglês
Izdano: S. Karger AG 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826449/
https://ncbi.nlm.nih.gov/pubmed/18322368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000113680
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