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The strength of transcription-factor binding modulates co-variation in transcriptional networks
An appreciable fraction of the transcriptome differs in level of expression among individuals. Transcription factor (TF) expression and DNA binding causes cell-specific activation and repression of downstream targets, and TF expression levels vary across individuals. However, it is not clear how the...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826431/ https://ncbi.nlm.nih.gov/pubmed/20080313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2009.12.005 |
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