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A General Framework for Formal Tests of Interaction after Exhaustive Search Methods with Applications to MDR and MDR-PDT

The initial presentation of multifactor dimensionality reduction (MDR) featured cross-validation to mitigate over-fitting, computationally efficient searches of the epistatic model space, and variable construction with constructive induction to alleviate the curse of dimensionality. However, the met...

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Detalhes bibliográficos
Main Authors: Edwards, Todd L., Turner, Stephen D., Torstenson, Eric S., Dudek, Scott M., Martin, Eden R., Ritchie, Marylyn D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826406/
https://ncbi.nlm.nih.gov/pubmed/20186329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009363
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