Dual mechanism of repression at a distance in the lac operon.
The mechanism by which the internal lacZ gene sequence O2 influences lac repression was investigated by using in vivo footprinting of operon mutants. Quantitative in vivo binding curves show that O2 strengthens by approximately 3-fold repressor binding to O1 that is located 400 base pairs upstream a...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1988
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282636/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3143112/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.8968 |
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