Axotomy-induced neurotrophic withdrawal causes the loss of phenotypic differentiation and downregulation of NGF signalling, but not death of septal cholinergic neurons

BACKGROUND: Septal cholinergic neurons account for most of the cholinergic innervations of the hippocampus, playing a key role in the regulation of hippocampal synaptic activity. Disruption of the septo-hippocampal pathway by an experimental transection of the fimbria-fornix drastically reduces the...

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Bibliografske podrobnosti
Main Authors: Lazo, Oscar M, Mauna, Jocelyn C, Pissani, Claudia A, Inestrosa, Nibaldo C, Bronfman, Francisca C
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826326/
https://ncbi.nlm.nih.gov/pubmed/20205865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-5
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