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Regeneration and reprogramming compared

BACKGROUND: Dedifferentiation occurs naturally in mature cell types during epimorphic regeneration in fish and some amphibians. Dedifferentiation also occurs in the induction of pluripotent stem cells when a set of transcription factors (Oct4, Sox2, Klf4 and c-Myc) is over expressed in mature cell t...

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Hlavní autoři: Christen, Bea, Robles, Vanesa, Raya, Marina, Paramonov, Ida, Belmonte, Juan Carlos Izpisúa
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826312/
https://ncbi.nlm.nih.gov/pubmed/20089153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-8-5
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