Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant

BACKGROUND: Optineurin is a multifunctional protein involved in several functions such as vesicular trafficking from the Golgi to the plasma membrane, NF-κB regulation, signal transduction and gene expression. Mutations in optineurin are associated with glaucoma, a neurodegenerative eye disease that...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Nagabhushana, Ananthamurthy, Chalasani, Madhavi L, Jain, Nishant, Radha, Vegesna, Rangaraj, Nandini, Balasubramanian, Dorairajan, Swarup, Ghanshyam
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826298/
https://ncbi.nlm.nih.gov/pubmed/20085643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-11-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados