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Growth factor receptor-bound protein-7 (Grb7) as a prognostic marker and therapeutic target in breast cancer

Background: Growth factor receptor-bound protein-7 (Grb7) is an adapter-type signaling protein recruited to various tyrosine kinases, including HER2/neu. Grb7-specific inhibitors are in early development. As with other targeted therapies, response to therapy might be associated with target expressio...

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Detalhes bibliográficos
Main Authors: Nadler, Y., González, A. M., Camp, R. L., Rimm, D. L., Kluger, H. M., Kluger, Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826097/
https://ncbi.nlm.nih.gov/pubmed/19717535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdp346
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