A Challenge Model for Shigella dysenteriae 1 in Cynomolgus Monkeys (Macaca fascicularis)

Shigella dysenteriae type 1 can cause devastating pandemics with high case fatality rates; a vaccine for Shigella is unavailable currently. Because of the risks associated with performing challenge studies with wild-type S. dysenteriae 1 in human clinical trials to advance vaccine development, an im...

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Main Authors: Shipley, Steven T, Panda, Aruna, Khan, Abdul Q, Kriel, Edwin H, Jr, Milton Maciel, Livio, Sofie, Nataro, James P, Levine, Myron M, Sztein, Marcelo B, DeTolla, Louis J
Format: Artigo
Sprog:Inglês
Udgivet: American Association for Laboratory Animal Science 2010
Fag:
Nonhuman Primate Models
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826086/
https://ncbi.nlm.nih.gov/pubmed/20158950
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