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A human 200-kDa protein binds selectively to DNA fragments containing G.T mismatches.
G.T mispairs, the sole mismatch type that can arise in "resting" mammalian DNA (through spontaneous hydrolytic deamination of 5-methylcytosine), are corrected in vivo with high efficiency and mostly to a G.C. We identified a protein factor, present in HeLa cell extracts, that binds selecti...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282606/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3194394/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.8860 |
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