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Predominant Clonal Accumulation of CD8(+) T Cells with Moderate Avidity in the Central Nervous Systems of Theiler's Virus-Infected C57BL/6 Mice

Induction of antigen-specific CD8(+) T cells bearing a high-avidity T-cell receptor (TCR) is thought to be an important factor in antiviral and antitumor immune responses. However, the relationship between TCR diversity and functional avidity of epitope-specific CD8(+) T cells accumulating in the ce...

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Detalles Bibliográficos
Main Authors: Kang, Hyun Seok, Kim, Byung S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826044/
https://ncbi.nlm.nih.gov/pubmed/20071578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01948-09
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