Identification of the CD163 Protein Domains Involved in Infection of the Porcine Reproductive and Respiratory Syndrome Virus

Scavenger receptor CD163 is a key entry mediator for porcine reproductive and respiratory syndrome virus (PRRSV). To identify the CD163 protein domains involved in PRRSV infection, deletion mutants and chimeric mutants were created. Infection experiments revealed that scavenger receptor cysteine-ric...

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Main Authors: Van Gorp, Hanne, Van Breedam, Wander, Van Doorsselaere, Jan, Delputte, Peter L., Nauwynck, Hans J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826032/
https://ncbi.nlm.nih.gov/pubmed/20032174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02093-09
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