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The smpB-ssrA Mutant of Yersinia pestis Functions as a Live Attenuated Vaccine To Protect Mice against Pulmonary Plague Infection

The bacterial SmpB-SsrA system is a highly conserved translational quality control mechanism that helps maintain the translational machinery at full capacity. Here we present evidence to demonstrate that the smpB-ssrA genes are required for pathogenesis of Yersinia pestis, the causative agent of pla...

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Autors principals: Okan, Nihal A., Mena, Patricio, Benach, Jorge L., Bliska, James B., Karzai, A. Wali
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825923/
https://ncbi.nlm.nih.gov/pubmed/20065026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00976-09
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