Increase in NF-κB Binding Affinity of the Variant C Allele of the Toll-Like Receptor 9 −1237T/C Polymorphism Is Associated with Helicobacter pylori-Induced Gastric Disease

Colonization of the gastric mucosa by Helicobacter pylori can lead to serious clinical outcomes, including gastric cancer. Toll-like receptors (TLRs) play an important role in the host response to H. pylori through the recognition of pathogen-associated molecular patterns. TLR9, in particular, is pa...

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Główni autorzy: Ng, Mike Tsz Hin, van't Hof, Rob, Crockett, Julie C., Hope, Mairi E., Berry, Susan, Thomson, John, McLean, Mairi H., McColl, Kenneth E. L., El-Omar, Emad M., Hold, Georgina L.
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology (ASM) 2010
Hasła przedmiotowe:
Bacterial Infections
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825916/
https://ncbi.nlm.nih.gov/pubmed/20038537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01226-09
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