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Development of inductively coupled plasma-mass spectrometry (ICP-MS) based protease assays

Rapid, sensitive and quantitative assays for proteases are important for drug development and in the diagnosis of disease. Here, an assay for protease activity which uses inductively coupled plasma-mass spectrometry (ICP-MS) detection is described. Peptidic α-chymotrypsin substrates were synthesized...

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Detalhes bibliográficos
Main Authors: Lathia, Urja S., Ornatsky, Olga, Baranov, Vladimir, Nitz, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825755/
https://ncbi.nlm.nih.gov/pubmed/19912984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2009.11.010
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