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Development of inductively coupled plasma-mass spectrometry (ICP-MS) based protease assays

Rapid, sensitive and quantitative assays for proteases are important for drug development and in the diagnosis of disease. Here, an assay for protease activity which uses inductively coupled plasma-mass spectrometry (ICP-MS) detection is described. Peptidic α-chymotrypsin substrates were synthesized...

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Bibliografiska uppgifter
Huvudupphovsmän: Lathia, Urja S., Ornatsky, Olga, Baranov, Vladimir, Nitz, Mark
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825755/
https://ncbi.nlm.nih.gov/pubmed/19912984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2009.11.010
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