Oxymatrine Downregulates TLR4, TLR2, MyD88, and NF-κB and Protects Rat Brains against Focal Ischemia

Inflammatory damage plays an important role in cerebral ischemic pathogenesis and may represent a target for treatment. Toll-like receptor-4 (TLR4), toll-like receptor-2 (TLR2), myeloid differentiation factor 88 (MyD88), and nuclear factor kappa-B (NF-κB) have been linked to inflammatory reactions....

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Hlavní autoři: Fan, Hongguang, Li, Litao, Zhang, Xiangjian, Liu, Ying, Yang, Chenhui, Yang, Yi, Yin, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825667/
https://ncbi.nlm.nih.gov/pubmed/20182634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/704706
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