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Human Negative Elongation Factor Activates Transcription and Regulates Alternative Transcription Initiation

The human negative elongation factor (NELF) is a four-subunit protein complex that inhibits the movement of RNA polymerase II (RNAPII) at an early elongation stage in vitro. NELF-mediated stalling of RNAPII also attenuates transcription of a number of inducible genes in human cells. To obtain a geno...

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Detalhes bibliográficos
Main Authors: Sun, Jianlong, Li, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825440/
https://ncbi.nlm.nih.gov/pubmed/20028984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.084285
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