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Human Negative Elongation Factor Activates Transcription and Regulates Alternative Transcription Initiation
The human negative elongation factor (NELF) is a four-subunit protein complex that inhibits the movement of RNA polymerase II (RNAPII) at an early elongation stage in vitro. NELF-mediated stalling of RNAPII also attenuates transcription of a number of inducible genes in human cells. To obtain a geno...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825440/ https://ncbi.nlm.nih.gov/pubmed/20028984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.084285 |
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