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Basis for the Isoform-specific Interaction of Myosin Phosphatase Subunits Protein Phosphatase 1c β and Myosin Phosphatase Targeting Subunit 1

Myosin II association with actin, which triggers contraction, is regulated by orchestrated waves of phosphorylation/dephosphorylation of the myosin regulatory light chain. Blocking myosin regulatory light chain phosphorylation with small molecule inhibitors alters the shape, adhesion, and migration...

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Autori principali: Scotto-Lavino, Elizabeth, Garcia-Diaz, Miguel, Du, Guangwei, Frohman, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825437/
https://ncbi.nlm.nih.gov/pubmed/20042605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074773
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