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Structure of GroEL in Complex with an Early Folding Intermediate of Alanine Glyoxylate Aminotransferase
Primary hyperoxaluria type 1 is a rare autosomal recessive disease caused by mutations in the alanine glyoxylate aminotransferase gene (AGXT). We have previously shown that P11L and I340M polymorphisms together with I244T mutation (AGXT-LTM) represent a conformational disease that could be amenable...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825432/ https://ncbi.nlm.nih.gov/pubmed/20056599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.062471 |
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