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Cross-talk between Remodeling and de Novo Pathways Maintains Phospholipid Balance through Ubiquitination
Phosphatidylcholine (PtdCho), the major phospholipid of animal membranes, is generated by its remodeling and de novo synthesis. Overexpression of the remodeling enzyme, LPCAT1 (acyl-CoA:lysophosphatidylcholine acyltransferase) in epithelia decreased de novo PtdCho synthesis without significantly alt...
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Format: | Artigo |
Sprache: | Inglês |
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American Society for Biochemistry and Molecular Biology
2010
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825420/ https://ncbi.nlm.nih.gov/pubmed/20018880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017350 |
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