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Role of Transmembrane Domain 4 in Ligand Permeation by Crithidia fasciculata Equilibrative Nucleoside Transporter 2 (CfNT2)

Equilibrative nucleoside transporters play essential roles in nutrient uptake, cardiovascular and renal function, and purine analog drug chemotherapies. Limited structural information is available for this family of transporters; however, residues in transmembrane domains 1, 2, 4, and 5 appear to be...

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Hlavní autoři: Arendt, Cassandra S., Ullman, Buddy
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825396/
https://ncbi.nlm.nih.gov/pubmed/20037157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074351
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