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Cyclic AMP-dependent phosphorylation of a brain inositol trisphosphate receptor decreases its release of calcium.

We report the stoichiometric phosphorylation of an inositol 1,4,5-trisphosphate receptor-binding protein from rat brain by the cAMP-dependent protein kinase but not by protein kinase C or Ca2+/calmodulin-dependent protein kinase. This phosphorylation event does not markedly alter [3H]inositol 1,4,5-...

Celý popis

Uloženo v:
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Supattapone, S, Danoff, S K, Theibert, A, Joseph, S K, Steiner, J, Snyder, S H
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1988
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282538/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2847175/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.22.8747
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