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The connecdenn DENN domain: a GEF for Rab35 mediating cargo-specific exit from early endosomes

The DENN domain is an evolutionarily ancient protein module. Mutations in the DENN domain cause developmental defects in plants and human diseases, yet the function of this common module is unknown. We now demonstrate that the connecdenn DENN domain functions as a guanine nucleotide exchange factor...

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Main Authors: Allaire, Patrick D., Marat, Andrea L., Dall’Armi, Claudia, Di Paolo, Gilbert, McPherson, Peter S., Ritter, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825348/
https://ncbi.nlm.nih.gov/pubmed/20159556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.12.037
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