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Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses

Interactions between the TNF-family receptor Fas (CD95) and Fas Ligand (FasL, CD178) can efficiently induce apoptosis and are critical for maintenance of immunological self-tolerance. FasL is kept under strict control by transcriptional and post-translational regulation. Surface FasL can be cleaved...

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Hlavní autoři: Ramaswamy, Madhu, Cleland, Sophia Y., Cruz, Anthony C., Siegel, Richard M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825281/
https://ncbi.nlm.nih.gov/pubmed/19132321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/400_2008_24
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