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Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses
Interactions between the TNF-family receptor Fas (CD95) and Fas Ligand (FasL, CD178) can efficiently induce apoptosis and are critical for maintenance of immunological self-tolerance. FasL is kept under strict control by transcriptional and post-translational regulation. Surface FasL can be cleaved...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825281/ https://ncbi.nlm.nih.gov/pubmed/19132321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/400_2008_24 |
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