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A Mechanism for the Polarity Formation of Chemoreceptors at the Growth Cone Membrane for Gradient Amplification during Directional Sensing

Accurate response to external directional signals is essential for many physiological functions such as chemotaxis or axonal guidance. It relies on the detection and amplification of gradients of chemical cues, which, in eukaryotic cells, involves the asymmetric relocalization of signaling molecules...

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Main Authors: Bouzigues, Cedric, Holcman, David, Dahan, Maxime
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825272/
https://ncbi.nlm.nih.gov/pubmed/20179770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009243
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