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Human Multipotent Stromal Cells (MSCs) Increase Neurogenesis and Decrease Atrophy of the Striatum in a Transgenic Mouse Model for Huntington's Disease

BACKGROUND: Implantation of human multipotent stromal cells from bone marrow (hMSCs) into the dentate gyrus of the hippocampus of mice was previously shown to stimulate proliferation, migration and neural differentiation of endogenous neural stem cells. We hypothesized that hMSCs would be beneficial...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Snyder, Brooke R., Chiu, Andrew M., Prockop, Darwin J., Chan, Anthony W. S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825266/
https://ncbi.nlm.nih.gov/pubmed/20179764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009347
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