Rapid activation of protein kinase C in isolated rat liver nuclei by prolactin, a known hepatic mitogen.

Rat liver nuclei pure by enzymatic and electron microscope criteria contain protein kinase C (PKC) that can be activated several hundredfold within 3 min of addition of prolactin or phorbol 12-tetradecanoate 13-acetate. Rat prolactin stimulated PKC maximally at 10(-12) M, whereas ovine prolactin was...

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Bibliografiske detaljer
Main Authors: Buckley, A R, Crowe, P D, Russell, D H
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC282517/
https://ncbi.nlm.nih.gov/pubmed/3186750
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