In vivo administration of artificial Antigen Presenting Cells activates low avidity T cells for treatment of cancer

The development of effective anti-tumor immune responses is normally constrained by low avidity, tumor-specific cytotoxic T lymphocytes (CTLs) which are unable to eradicate the tumor. Strategies to rescue anti-tumor activity of low avidity melanoma-specific CTLs in vivo may improve immunotherapy eff...

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Main Authors: Ugel, Stefano, Zoso, Alessia, De Santo, Carmela, Li, Yu, Marigo, Ilaria, Zanovello, Paola, Scarselli, Elisa, Cipriani, Barbara, Oelke, Mathias, Schneck, Jonathan P., Bronte, Vincenzo
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825113/
https://ncbi.nlm.nih.gov/pubmed/19934317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0400
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