Klinefelter’s Syndrome, 47,XXY, in Male Systemic Lupus Erythematosus Supports a Gene Dose Effect from the X Chromosome

BACKGROUND: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that predominantly affects women. Despite Klinefelter's syndrome (47,XXY) and SLE coexisting in isolated cases, no association has been established with SLE or any other autoimmune disease. Methods: Sex chromosome g...

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Hauptverfasser: Scofield, R. Hal, Bruner, Gail R., Namjou, Bahram, Kimberly, Robert P., Ramsey-Goldman, Rosalind, Petri, Michelle, Reveille, John D., Alarcon, Graciela S., Vila, Luis M., Reid, Jeff, Harris, Bryan, Li, Shibo, Kelly, Jennifer A., Harley, John B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824898/
https://ncbi.nlm.nih.gov/pubmed/18668569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23701
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