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SUMOylation regulates the nuclear mobility of CREB binding protein and its association with nuclear bodies in live cells

The lysine acetyltransferase CREB binding protein (CBP) is required for chromatin modification and transcription at many gene promoters. In fixed cells, a large proportion of CBP colocalises to PML or nuclear bodies. Using live cell imaging, we show here that YFP-tagged CBP expressed in HEK293 cells...

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Bibliographic Details
Main Authors: Ryan, Colm M., Kindle, Karin B., Collins, Hilary M., Heery, David M.
Format: Artigo
Language:Inglês
Published: Academic Press 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824845/
https://ncbi.nlm.nih.gov/pubmed/20006587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.12.040
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