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ASCL1 Regulates Expression of the CHRNA5/A3/B4 Lung Cancer Susceptibility Locus

Tobacco contains a variety of carcinogens as well as the addictive compound nicotine. Nicotine addiction begins with the binding of nicotine to its cognate receptor, the nicotinic acetylcholine receptor (nAChR). Genome-wide association studies have implicated the nAChR gene cluster, CHRNA5/A3/B4, in...

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Detalhes bibliográficos
Main Authors: Improgo, Ma. Reina D., Schlichting, Nicolette A., Cortes, Roxana Y., Zhao-Shea, Rubing, Tapper, Andrew R., Gardner, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824774/
https://ncbi.nlm.nih.gov/pubmed/20124469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0185
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