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Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin.

To investigate the role of different cysteine residues in bovine rhodopsin, a series of mutants were prepared in which the cysteine residues were systematically replaced by serines. The mutant genes were expressed in monkey kidney cells (COS-1) and the mutant opsins were evaluated for their levels o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Karnik, S S, Sakmar, T P, Chen, H B, Khorana, H G
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282477/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3186735/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.22.8459
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