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Arterivirus Nsp1 Modulates the Accumulation of Minus-Strand Templates to Control the Relative Abundance of Viral mRNAs

The gene expression of plus-strand RNA viruses with a polycistronic genome depends on translation and replication of the genomic mRNA, as well as synthesis of subgenomic (sg) mRNAs. Arteriviruses and coronaviruses, distantly related members of the nidovirus order, employ a unique mechanism of discon...

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Autores principales: Nedialkova, Danny D., Gorbalenya, Alexander E., Snijder, Eric J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824749/
https://ncbi.nlm.nih.gov/pubmed/20174607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000772
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