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Targeted Expression of SV40 Large T-antigen to Visceral Smooth Muscle Induces Proliferation of Contractile Smooth Muscle Cells and Results in Megacolon

Many pathological conditions result from the proliferation and de-differentiation of smooth muscle cells leading to impaired contractility of the muscle. Here we show that targeted expression of SV40 large T-antigen to visceral smooth muscle cells in vivo results in increased smooth muscle cell prol...

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Detalhes bibliográficos
Main Authors: Herring, B. Paul, Hoggatt, April M., Smith, Aiping F., Gallagher, Patricia J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824515/
https://ncbi.nlm.nih.gov/pubmed/10364214
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