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DIFFERENTIATION-INDUCING POTENCY OF THE SECO-STEROID JK-1624F2-2 CAN BE INCREASED BY COMBINATION WITH AN ANTIOXIDANT AND A p38 MAPK INHIBITOR WHICH UPREGULATES THE JNK PATHWAY
Low calcemic analogs of vitamin D are candidates for differentiation therapy of human myeloid leukemias. We report here that the seco-steroid synthesized to have resistance to intracellular degradation and low calcemia-inducing activity, 1alpha-hydroxymethyl-3beta-16-ene-24,24-difluoro-25-hydroxy-vi...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824509/ https://ncbi.nlm.nih.gov/pubmed/17583492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2007.01.003 |
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