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A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway

Genetic screens in the yeast Saccharomyces cerevisiae have identified many proteins involved in the secretory pathway, most of which have orthologues in higher eukaryotes. To investigate whether there are additional proteins that are required for secretion in metazoans but are absent from yeast, we...

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Detalhes bibliográficos
Main Authors: Wendler, Franz, Gillingham, Alison K, Sinka, Rita, Rosa-Ferreira, Cláudia, Gordon, David E, Franch-Marro, Xavier, Peden, Andrew A, Vincent, Jean-Paul, Munro, Sean
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824459/
https://ncbi.nlm.nih.gov/pubmed/19942856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.350
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