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ArfGAP1 generates an Arf1 gradient on continuous lipid membranes displaying flat and curved regions
ArfGAP1, which promotes GTP hydrolysis on the small G protein Arf1 on Golgi membranes, interacts preferentially with positively curved membranes through its amphipathic lipid packing sensor (ALPS) motifs. This should influence the distribution of Arf1-GTP when flat and curved regions coexist on a co...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824456/ https://ncbi.nlm.nih.gov/pubmed/19927117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.341 |
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