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Optimized detection of sequence variation in heterozygous genomes using DNA microarrays with isothermal-melting probes
The use of DNA microarrays to identify nucleotide variation is almost 20 years old. A variety of improvements in probe design and experimental conditions have brought this technology to the point that single-nucleotide differences can be efficiently detected in unmixed samples, although developing r...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824413/ https://ncbi.nlm.nih.gov/pubmed/20080586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913883107 |
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