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Lack of evolvability in self-sustaining autocatalytic networks constraints metabolism-first scenarios for the origin of life

A basic property of life is its capacity to experience Darwinian evolution. The replicator concept is at the core of genetics-first theories of the origin of life, which suggest that self-replicating oligonucleotides or their similar ancestors may have been the first “living” systems and may have le...

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Main Authors: Vasas, Vera, Szathmáry, Eörs, Santos, Mauro
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824406/
https://ncbi.nlm.nih.gov/pubmed/20080693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912628107
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