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ATM is down-regulated by N-Myc–regulated microRNA-421

Ataxia-telangiectasia mutated (ATM) is a high molecular weight protein serine/threonine kinase that plays a central role in the maintenance of genomic integrity by activating cell cycle checkpoints and promoting repair of DNA double-strand breaks. Little is known about the regulatory mechanisms for...

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Bibliographische Detailangaben
Hauptverfasser: Hu, Hailiang, Du, Liutao, Nagabayashi, Gindy, Seeger, Robert C., Gatti, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824372/
https://ncbi.nlm.nih.gov/pubmed/20080624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907763107
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