Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation

Self-renewal and differentiation of embryonic stem cells (ESCs) are controlled by intracellular transcriptional factors and extracellular factor-activated signaling pathways. Transcription factor Oct4 is a key player maintaining ESCs in an undifferentiated state, whereas the Erk/MAPK pathway is know...

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Hlavní autoři: Li, Lingjie, Sun, Lei, Gao, Furong, Jiang, Jing, Yang, Ying, Li, Chunliang, Gu, Junjie, Wei, Zhe, Yang, Acong, Lu, Rui, Ma, Yu, Tang, Fan, Won Kwon, Sung, Zhao, Yingming, Li, Jinsong, Jin, Ying
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824367/
https://ncbi.nlm.nih.gov/pubmed/20080709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905657107
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