Manipulation of stretch-induced atriopeptin prohormone release and processing in the perfused rat heart.

Atriopeptin (AP) is stored as the prohormone AP-126 [atrial natriuretic factor-(1-26)] in atrial granules. Cultured atrial myocytes synthesize and release only prohormone into the medium. HPLC analysis of the coronary venous effluent of media from perfused rat hearts subjected to right atrial stretc...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Ito, T, Toki, Y, Siegel, N, Gierse, J K, Needleman, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282436/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2973064/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.8365
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