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Neuregulin 1 regulates pyramidal neuron activity via ErbB4 in parvalbumin-positive interneurons

Neuregulin 1 (NRG1) is a trophic factor thought to play a role in neural development. Recent studies suggest that it may regulate neurotransmission, mechanisms of which remain elusive. Here we show that NRG1, via stimulating GABA release from interneurons, inhibits pyramidal neurons in the prefronta...

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Detalhes bibliográficos
Main Authors: Wen, Lei, Lu, Yi-Sheng, Zhu, Xin-Hong, Li, Xiao-Ming, Woo, Ran-Sook, Chen, Yong-Jun, Yin, Dong-Min, Lai, Cary, Terry, Alvin V., Vazdarjanova, Almira, Xiong, Wen-Cheng, Mei, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824309/
https://ncbi.nlm.nih.gov/pubmed/20080551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910302107
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