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Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice
Reduced function of the N-methyl-D-aspartate receptor (NMDAR) has been implicated in the pathophysiology of schizophrenia. The NMDAR contains a glycine binding site in its NR1 subunit that may be a useful target for the treatment of schizophrenia. In this study, we assessed the therapeutic potential...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824030/ https://ncbi.nlm.nih.gov/pubmed/19751394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2009.00529.x |
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