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A NOVEL COMPOSITE IMMUNOTOXIN THAT SUPPRESSES RABIES VIRUS PRODUCTION BY THE INFECTED CELLS

Using Strepavidin as a scaffold, we have assembled a composite immunotoxin that consists of recombinant Pseudomonas exotoxin A subunit (PE38) and recombinant 25-D1.16 Fab fragment which recognizes the SIINFEKL (pOV8) peptide from ovalbumin in association with H-2K(b) MHC class I protein. The composi...

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Autors principals: Mareeva, Tatiana, Wanjalla, Celestine, Schnell, Matthias J., Sykulev, Yuri
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823984/
https://ncbi.nlm.nih.gov/pubmed/19932697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2009.11.010
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