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Involvement of stromal p53 in tumor-stroma interactions

p53 is a major tumor-suppressor gene, inactivated by mutations in about half of all human cancer cases, and probably incapacitated by other means in most other cases. Most research regarding the role of p53 in cancer has focused on its ability to elicit apoptosis or growth arrest of cells that are p...

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Bibliographic Details
Main Authors: Bar, Jair, Moskovits, Neta, Oren, Moshe
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823948/
https://ncbi.nlm.nih.gov/pubmed/19914385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2009.11.006
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