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PR65, the HEAT-repeat scaffold of phosphatase PP2A, is an elastic connector that links force and catalysis
PR65 is the two-layered (α-α solenoid) HEAT-repeat (Huntingtin, elongation factor 3, a subunit of protein phosphatase 2A, PI3 kinase target of rapamycin 1) scaffold of protein phosphatase PP2A. Molecular dynamics simulations predict that, at forces expected in living systems, PR65 undergoes (visco-)...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823866/ https://ncbi.nlm.nih.gov/pubmed/20133745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914073107 |
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