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Frequency and spectrum of mutations produced by a single cis-syn thymine-thymine cyclobutane dimer in a single-stranded vector.

We have constructed a single-stranded vector that contains a uniquely located cis-syn T-T cyclobutane dimer by ligating a synthetic oligomer containing this UV photoproduct into M13mp7 viral DNA linearized with EcoRI. In the absence of SOS induction, transfection of a uvrA6 mutant of Escherichia col...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Banerjee, S K, Christensen, R B, Lawrence, C W, LeClerc, J E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282379/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3054882/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.8141
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